Corning 384 Well Black Clear Square Bottom Plasma Treated, Micro-Cavity Plate, 200um Wide and 100um Depth, Ind. Packaged, with Lid, 1/5 (C062B-040627)

With the effectiveness of 3D spheroids in many areas of research including anti-cancer drug screening and in vitro tumor studies, the need for better methods to produce replicate spheroids of uniform size in mass quantities has emerged. Corning Elplasia plates address this need by enabling researchers to generate a high density of spheroids in a scaffold-free model. Use Corning Elplasia plates to generate, culture, and analyze your spheroids all in a standard plate footprint. Corning Elplasia plates are available in multiple formats, two well geometry types, and two surface coatings.

Corning Elplasia Round Bottom Plates
Corning Elplasia round bottom plates are optimal for bulk spheroid formation, assay, expansion, and collection. Round bottom plates are available in 6-, 24-, and 96-well formats and all feature Corning Ultra-Low Attachment (ULA) surface. Corning ULA surface is a proprietary, animal-free, covalently bonded hydrogel surface that is hydrophilic and neutrally charged. The ULA surface promotes the formation and easy harvesting of anchorage-dependent scaffoldfree spheroids.

Corning Elplasia Square Bottom Type Plates
Corning Elplasia square bottom type plates feature a surface with optical qualities suited for image analysis, making them an ideal solution for clonal selection and high magnification imaging of very small clusters. Square bottom plates are plasma-treated for self-coating and are available in 6-, 24-, 96-, and 384-well formats.

Corning® Elplasia® plates are compatible with many cell types and may be used across many applications including:
• Drug screening/High throughput screening
• Cancer/Tumor biology
• Stem cell biology
• Cell therapy research
• 3D tissue engineering

Key Features:
• Available in two well geometry and surface coating options: round bottom type featuring Ultra Low Attachment (ULA) surface and square bottom type featuring a plasma-treated surface for self-coating
•Multiple format options: 6-, 24-, 96-, and 384-well
• Black opaque sidewalls that reduce well-to-well cross-talk
• Square well plates feature a surface with optical qualities suited for image analysis
• Gamma irradiated
• One-year shelf life

Key Benefits:
• Create uniform spheroid formation at large volumes with a simple and easy to use plug and play protocol
• No rinsing required prior to seeding
• Generate and culture spheroids in one plate - for up to 21 or more days
• Highly reproducible bulk spheroid formation across microcavity wells - from 79 to 15,000+ spheroids per well
• Culture a high density of spheroids in one plate under one culture condition
• Increased signal per well without an increase in spheroid size
• High density format also generates increased data points, enabling image analysis of multiple spheroids vs. one spheroid per well
• Suitable for fluorescent/luminescent assays
• The square well plates are ideal for clonal selection and high magnification imaging of very small clusters
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