CONGO RED BIOXTRA CERTIFIED BY THE BIOLOGICAL STAIN COMMISSION (C005B-049647)

Application

Congo red has been used for the staining of β amyloid peptides.

Biochem/physiol Actions

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Suitability

Certified for use as a counterstain for alum based hematoxylin and in the Highman or the Churukian modification of Puchtler′s amyloid stain.

Molecular Weight: 696.66. Empirical Formula: C₃₂H₂₂N₆Na₂O₆S₂. grade: certified by the Biological Stain Commission. Quality Level: 200. product line: BioXtra. form: powder. composition: Dye content, ≥. 85% . mp: >. 360 . °C (lit.). solubility: H₂O: 10 . mg/mL. application(s): diagnostic assay manufacturing
hematology
histology. storage temp.: room temp. SMILES string: [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(: O): O)\N: N\c3ccc(cc3)-c4ccc(cc4)\N: N\c5cc(c6ccccc6c5N)S([O-])(: O): O. InChI: 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34. . /h1-18H,33-34H2,(H,39,40,41)(H,42,43,44). . /q. 2*+1/p-2/b37-35+,38-36+. . . InChI key: IQFVPQOLBLOTPF-HKXUKFGYSA-L. Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H350 - H361d. Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501. Hazard Classifications: Carc. 1B - Repr. 2. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Personal Protective Equipment: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges.