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compound 48/80 (c15-1346-443)

COMPOUND 48/80 (C005B-103948)

Catalog No.
C005B-103948
Manufacturer No.
C2313-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG

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Compound 48/80, is the condensation product of N -methyl p -methoxyphenethylamine and formaldehyde. Application Compound 48/80 has been used: to stimulate hemocytes for histamine release for measurement in ELISA and flow cytometry to induce mast

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General description

Compound 48/80, is the condensation product of N-methyl p-methoxyphenethylamine and formaldehyde.

Application

Compound 48/80 has been used:

  • to stimulate hemocytes for histamine release for measurement in ELISA and flow cytometry
  • to induce mast cell degranulation
  • to induce anaphylactic activity, dermatitis, pruritis, inflammation in mice

Biochem/physiol Actions

Compound 48/80 (C 48/80) is a hypotensive agent, which promotes release of histamine. C 48/80 reduces the phagocytic ability of hemocytes in Styela plicata. C 48/80 promotes degranulation of mast cells. It Inhibits calmodulin, phospholipase C, endoplasmic reticulum (ER) Ca2+ ATPase and activates G proteins.

Preparation Note

Condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde.

form: powder. Quality Level: 200. solubility: H2O: 50 . mg/mL. storage temp.: −. 20°C. Pictograms: GHS06. Signal Word: Danger. Hazard Statements: H301 + H311 + H331. Precautionary Statements: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311. Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges.
UPC:
12352105
Condition:
New
HazmatClass:
Yes
MPN:
C2313-100MG

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