CIS-DIAMINEPLATINUM(II) DICHLORIDE >=99.9% TRACE METALS BASIS (C005B-020243)

Application

cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.

Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer.

Biochem/physiol Actions

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

Molecular Weight: 300.05. Empirical Formula: H₆Cl₂N₂Pt. linearFormula: Pt(NH₃)₂Cl₂. Quality Level: 100. Assay: ≥. 99.9% trace metals basis. reaction suitability: core: platinum, reagent type: catalyst. mp: 270 . °C (lit.). antibiotic activity spectrum: neoplastics. Mode of action: DNA synthesis | interferes. SMILES string: N.N.Cl[Pt]Cl. InChI: 1S/2ClH.2H3N.Pt/h2*1H. 2*1H3. /q. . . . +2/p-2. InChI key: LXZZYRPGZAFOLE-UHFFFAOYSA-L. Pictograms: GHS06,GHS08. Signal Word: Danger. Hazard Statements: H300 - H315 - H317 - H319 - H334 - H335 - H350. Precautionary Statements: P202 - P261 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.