CINACIGUAT HYDROCHLORIDE (C005B-311973)

Catalog No.: C005B-311973
Manufacturer No.: SML1532-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Biochem/physiol Actions Cinaciguat activates sGC (soluble guanylate cyclase) independently of NO. Cinaciguat binds to sGC′:s NO-sensory H-NOX domain when it is heme-depleted.

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Description
Specifications

Biochem/physiol Actions

Cinaciguat activates sGC (soluble guanylate cyclase) independently of NO. Cinaciguat binds to sGC′s NO-sensory H-NOX domain when it is heme-depleted. Also, the compound Cinaciguat protects sGC from oxidation-induced ubiquitin-triggered degradation.

Cinaciguat, also known as BAY 58-2667, is a novel activator of guanylate cyclase. It is used in the treatment of acute decompensated heart failure (ADHF). It has been reported that cinaciguat possesses cardiovascular effects.

UPC:: 51172111
Condition:: New
HazmatClass:: No
MPN:: SML1532-5MG
CAS:: 646995-35-9

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