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ciglitizone

CIGLITIZONE >=98% (HPLC)

Catalog No.
C005B-076394
Manufacturer No.
C3974-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG

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Application Ciglitizone has been used as a proliferator-activated receptor γ (PPARγ) agonist: to study its effects on cell proliferation in human melanocytes to study its effects on pigmentation and migration of human melanocytes It also

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Application

Ciglitizone has been used as a proliferator-activated receptor γ (PPARγ) agonist:

  • to study its effects on cell proliferation in human melanocytes
  • to study its effects on pigmentation and migration of human melanocytes

It also may be used to study its effects on cell cycle and apoptosis in monocytic cells.

Biochem/physiol Actions

Ciglitizone belongs to the class of thiazolidinediones and is a peroxisome proliferator-activated receptor γ (PPARγ) agonist. It exhibits anti-diabetic activity. Ciglitizone has the potential to treat tumor necrosis factor α (TNFα)-related apoptosis-inducing ligand (TRAIL)-refractory high-grade urothelial cancers.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Molecular Weight: 333.45. Empirical Formula: C18H23NO3S. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. originator: Takeda. SMILES string: CC1(CCCCC1)COc2ccc(CC3SC(: O)NC3: O)cc2. InChI: 1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21). InChI key: YZFWTZACSRHJQD-UHFFFAOYSA-N. Gene Information: human ... PPARG(5468)
mouse ... Pparg(19016). Storage Class Code: 10 - Combustible liquids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US).
UPC:
51171807
Condition:
New
HazmatClass:
No
MPN:
C3974-5MG
CAS:
74772-77-3

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