CID755673 (C005B-313910)

Catalog No.: C005B-313910
Manufacturer No.: SML0003-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Application CID755673 was used to study the role of PKD in dendrite retraction in mouse Purkinje cells. Biochem/physiol Actions CID755673 is a cell-permeable, potent and selective inhibitor of all three protein kinase D (PKD) isoforms PKD1

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Description
Specifications

Application

CID755673 was used to study the role of PKD in dendrite retraction in mouse Purkinje cells.

Biochem/physiol Actions

CID755673 is a cell-permeable, potent and selective inhibitor of all three protein kinase D (PKD) isoforms PKD1 (PKCμ), PKD2, and PKD3 (PKCν). CID755673 is not competitive with ATP.

CID755673 was not suitable to inhibit PKD in Swiss 3T3 cells as it utilizes PKD-dependent pathway to enhance the mitogenic signaling triggered by EGF, phorbol esters and bombesin. It should, therefore, be used with caution.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:: 85101506
Condition:: New
HazmatClass:: No
MPN:: SML0003-25MG
CAS:: 521937-07-5

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