Totrombopag is an orally effective thrombopoietin receptor ( TpoR ) agonist. By activating TpoR , Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5 , a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology .
Molecular Formula: C25H22N8O2
Molecular Weight: 466.5
PubChem CID: 135871124
- UPC:
- 85101506
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C1283485-1mg
- Product Size:
- 1mg
- CAS:
- 376592-42-6
akash.verma@cenmed.com
(732) 447-1115





