THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC 50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines .
Specification: ≥99%
Molecular Formula: C31H29N7O2
Molecular Weight: 531.600
PubChem CID: 134451950
- UPC:
- 41105508
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C954977-1mg
- Product Size:
- 1mg
- CAS:
- 2058075-45-7
akash.verma@cenmed.com
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