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cibacron blue 3g-a

CIBACRON BLUE 3G-A

Catalog No.
C005B-082324
Manufacturer No.
B1064-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR

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Application When immobilized using an insoluble porous support matrix such as agarose, Cibacron Blue 3GA is used for affinity chromatography purification of enzymes. This affinity has been attributed to a structural similarity between the dye and

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Application

When immobilized using an insoluble porous support matrix such as agarose, Cibacron Blue 3GA is used for affinity chromatography purification of enzymes. This affinity has been attributed to a structural similarity between the dye and the natural ligands for proteins with cofactor binding domains.

Biochem/physiol Actions

Cibacron Blue 3GA is an anionic anthraquinone dye. It acts as a P2-purinoceptor antagonist and inhibits stimulus-evoked glutamate release by rat brain cortical tissue. Cibacron Blue 3GA inhibits OXA-1 and OXA-2 β-lactamases and was used to observe the binding of ligands to OXA-1 β-lactamase by monitoring tryptophan fluorescence.

Molecular Weight: 774.16. Empirical Formula: C29H20ClN7O11S3. form: powder. Quality Level: 200. solubility: H2O: 10 . mg/mL, blue. application(s): diagnostic assay manufacturing
hematology
histology. storage temp.: room temp. SMILES string: Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccccc4S(O)(: O): O)n3)c(c2)S(O)(: O): O)c5C(: O)c6ccccc6C(: O)c15)S(O)(: O): O. InChI: 1S/C29H20ClN7O11S3/c30-27-35-28(33-16-7-3-4-8-19(16)49(40,41)42)37-29(36-27)34-17-10-9-13(11-20(17)50(43,44)45)32-18-12-21(51(46,47)48)24(31)23-22(18)25(38)14-5-1-2-6-15(14)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37). InChI key: YKCWQPZFAFZLBI-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
51141513
Condition:
New
HazmatClass:
No
MPN:
B1064-1G
CAS:
84166-13-2

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