General description
Chloramine-T trihydrate is a widely used oxidizing agent in organic synthesis. It acts as a source of halonium cation and nitrogen anion and thus acts as a base and nucleophile. Due to its reactivity with a wide range of functional groups, it is involved in different molecular transformations. It is effective in acidic, neutral, and basic conditions.
Application
Chloramine-T trihydrate can be used as:
- A reagent for chlorination in drinking water treatment.
- A dehydrogenating agent for the oxidative dehydrogenation of aromatic aldehyde phenylhydrazones to synthesize nitrile imines.
- The nitrene source for the aziridination of alkenes and the amidation of cyclic ethers.
Molecular Weight: 281.69. Empirical Formula: C
7H
7ClNNaO
2S · 3H
2O. linearFormula: CH
3C
6H
4SO
2NClNa · 3H
2O. Agency: USP/NF, reag. Ph. Eur.. Quality Level: 100. Assay: 98.0-103.0%. impurities: ≤. 1.5% insoluble in ethanol. pH: 8-10 (20 . °C, 5%). mp: 167-170 . °C (lit.). SMILES string: O.O.O.Cc1ccc(cc1)S(: O)(: O)N([Na])Cl. InChI: 1S/C7H7ClNO2S.Na.3H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8. . . . /h2-5H,1H3. . 3*1H2/q-1. +1. . . . InChI key: NZYOAGBNMCVQIV-UHFFFAOYSA-N. Pictograms: GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H302 - H314 - H334. Precautionary Statements: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B. Supp Hazards: EUH031. Storage Class Code: 8A - Combustible, corrosive hazardous materials. WGK: WGK 2. Flash Point(F): 377.6 °F - closed cup. Flash Point(C): 192 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.