A bile acid and FXR ligand (EC50 = 13-34 &muM) that is a key regulator of cholesterol homeostasis exhibits toxicity that is linked to increased glutathione and increased oxidative stress excess CDCA contributes to liver and intestinal cancers.
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A bile acid and FXR ligand (EC50 = 13-34 μM) that is a key regulator of cholesterol homeostasis; exhibits toxicity that is linked to increased glutathione and increased oxidative stress; excess CDCA contributes to liver and intestinal cancers.
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