CEFTOLOZANE SULFATE (C005B-475254)

Catalog No.: C005B-475254
Manufacturer No.: SBR00048-2MG
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: EA

General description Ceftolozane is a novel oxyimino-aminothiazolyl cephalosporin compound. It was formerly known as CXA-101 and FR264205.

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Description
Specifications

General description

Ceftolozane is a novel oxyimino-aminothiazolyl cephalosporin compound. It was formerly known as CXA-101 and FR264205. Ceftolozane is structurally similar to ceftazidime with an amino-thiadiazole ring on the 7-position side chain.

Biochem/physiol Actions

Ceftolozane is an antipseudomonal β-lactam inhibitor. It is also a PBP3 inhibitor with a higher affinity for PBP1b compared with other β-lactam inhibitors. Ceftolozane is stable in human plasma, but a low plasma protein binding (20%). It is primarily excreted through urine unchanged. Ceftolozane is a potent antibiotic against Gram-negative bacteria like P. aeruginosa, and Enterobacteriaceae.

UPC:: 12161910
Condition:: New
HazmatClass:: No
MPN:: SBR00048-2MG
CAS:: 936111-69-2

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