CEFTAZIDIME HYDRATE 90.0-105.0 % (C005B-011337)

General description

Broad spectrum antibiotic; third generation cephalosporin

Chemical structure: ß-lactam

Application

Ceftazidime hydrate is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP3 on bacterial cell wall mucopeptide synthesis. It is also used in bacterial susceptibility studies and to select mutant colonies of interest.

Biochem/physiol Actions

Cephalosporins, such as ceftazidime , disrupt the synthesis of the peptidoglycan layer of bacterial cell walls.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Molecular Weight: 546.58 (anhydrous basis). Empirical Formula: C₂₂H₂₂N₆O₇S₂ · xH₂O. Quality Level: 200. Assay: 90.0-105.0%. form: powder or crystals. contains: ~10% sodium carbonate as stabilizer. antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria. Mode of action: cell wall synthesis | interferes. storage temp.: 2-8°C. SMILES string: [H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(C)(O\N: C(/C(: O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3): C(N2C1: O)C([O-]): O)c4csc(N)n4)C(O): O. InChI: 1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27. . . . . /h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34). 5*1H2/b26-13-. . . . . /t14-,18-. . . . . /m1...../s1. InChI key: NMVPEQXCMGEDNH-TZVUEUGBSA-N. Pictograms: GHS08. Signal Word: Danger. Hazard Statements: H317 - H319 - H334. Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves.