Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3, Phase 3.
Specifications and Purity: ≥98%
Molecular Formula: C25H27FN4O3
Molecular Weight: 450.52
PubChem CID: 9933475
Isomeric SMILES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/C125911-SCI_4e89510b05b613869f01babaf8b54e3b.pdf
- UPC:
- 51111606
- Condition:
- New
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- C125911-10mg
- CAS:
- 288383-20-0
- Health Hazards:
- Toxic
- Product Size:
- 10mg
- Hazard Statement Codes:
- H312:H301
- Precautionary Statement Codes:
- P501:P405:P362+P364:P302+P352:P391:P330:P280:P273:P270:P264:P260
akash.verma@cenmed.com
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