CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The K i values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC 50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer , deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infectionIn VitroCB2R/FAAH modulator-3 (compound 27)(10 μM) reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β and IL6 in unstimulated monocytes and macrophages. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:CB1 67.6 nM (Ki) CB2 20.1 nM (Ki).
Specifications and Purity: ≥99%
Molecular Formula: C22H31NO2
Molecular Weight: 341.49
- UPC:
- 12141730
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C646918-5mg
- CAS:
- 2876918-67-9
- Product Size:
- 5mg
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