General description
A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).
A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Sequence
Ac-Trp-Glu-His-Asp-AMC
Other Notes
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 784.77. Empirical Formula: C38H40N8O11. Quality Level: 100. Assay: ≥. 95% (HPLC). form: lyophilized. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze, desiccated, protect from light. solubility: DMSO: 5 . mg/mL. fluorescence: λ. ex . 365–380 . nm, λ. em . 430–460 . nm. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 12352318
- Condition:
- New
- HazmatClass:
- No
- MPN:
- 218739-5MG
akash.verma@cenmed.com
(732) 447-1115





