CARDIOLIPIN FROM BOVINE HEART SODIUM >=97% (TLC) (C005B-103785)

General description

Cardiolipin is localized in the inner membrane of mitochondria. It contains 18 carbon atoms, 3-phosphatidyl groups connected via a glycerol bridge. Cardiolipin is an important component of ATP synthase enzyme.

Application

Cardiolipin sodium salt from bovine heart has been used:

• as a phospholipid standard in thin layer chromatography for the quantification of total mitochondrial lipids of Neurospora crassa(89)
• as an internal standard in reverse phase high performance liquid chromatography (RP-HPLC) for quantification of bacterial lipid extracts(90)
• as an antigen to evaluate IgM reaction in systemic lupus erythematosus (SLE) patients(91)

Biochem/physiol Actions

Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component. Inhibits cell attachment of fibronectin, vitronectin and Type I collagen.

Packaging

packaged under argon

biological source: bovine heart. Quality Level: 200. Assay: ≥. 97% (TLC). form: lyophilized powder. lipid type: phosphoglycerides. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).