CANTHARIDIN (C005B-048923)

General description

Cantharidin is a poisonous vesicant, which is produced by blister bees. It is used to treat piles, ulcers, venomous worms and tuberculous scrofuloderma. It is used as an aphrodisiac, abortifacient and a veterinary medicine diuretic.

Application

Cantharidin has been used to inhibit protein phosphatase 2 (PP2A).

Biochem/physiol Actions

Inhibitor of protein phosphatase 2A.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Molecular Weight: 196.20. Empirical Formula: C₁₀H₁₂O₄. Quality Level: 200. color: white. mp: 215-217 . °C (lit.), 215-218 . °C. solubility: DMSO: soluble, ethanol: soluble. SMILES string: C[C@]12C3CCC(O3)[C@@]1(C)C(: O)OC2: O. InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-. InChI key: DHZBEENLJMYSHQ-XCVPVQRUSA-N. Gene Information: human ... PPP2CA(5515), PPP2CB(5516), PPP2CBP(5517), PPP2R1A(5518), PPP2R1B(5519), PPP2R2A(5520), PPP2R2B(5521), PPP2R2C(5522), PPP2R3A(5523), PPP2R5A(5525). Pictograms: GHS06. Signal Word: Danger. Hazard Statements: H300 - H315 - H319 - H335. Precautionary Statements: P261 - P264 - P270 - P301 + P310 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.