CAMK2? ACTIVE HUMAN GST TAGGED (C005B-103799)

Biochem/physiol Actions

CAMK2γ is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2γ has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMK2γ showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

recombinant: expressed in baculovirus infected Sf9 cells. Quality Level: 200. product line: PRECISIO^®. Kinase. Assay: ≥. 70% (SDS-PAGE). form: buffered aqueous glycerol solution. specific activity: 211-285 . nmol/min·mg. mol wt: ~60 . kDa. UniProt accession no.: Q13555. shipped in: dry ice. storage temp.: −. 70°C. Gene Information: human ... CAMK2G(818). Storage Class Code: 10 - Combustible liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.