Application
Cafestol acetate has been used to determine the effects of coffee on heat shock response (HSR).
Biochem/physiol Actions
Cafestol is a coffee-specific diterpene. It has anti-carcinogenic and anti-inflammatory activities. Cafestol stimulates apoptosis in cells associated with colorectal and renal cancer (Caki cells). It is used to study mechanisms of anti-oxidation related to hydrogen peroxide induced oxidative stress and DNA damage. Cafestol increases the level of glutathione (GSH), by stimulating γ-glutamylcysteine synthetase. It acts as a chemopreventive agent by inducing cytochrome P-450.
Other Notes
Furan-containing diterpene from green coffee beans.
Molecular Weight: 358.47. Empirical Formula: C22H30O4. Quality Level: 100. Assay: ≥. 98%. form: powder. technique(s): HPLC: suitable. color: white to off-white. storage temp.: 2-8°C. SMILES string: CC(: O)OCC1(O)CC23CCC4c5ccoc5CCC4(C)C2CCC1C3. InChI: 1S/C22H30O4/c1-14(23)26-13-22(24)12-21-9-5-17-16-7-10-25-18(16)6-8-20(17,2)19(21)4-3-15(22)11-21/h7,10,15,17,19,24H,3-6,8-9,11-13H2,1-2H3. InChI key: PTGGVIKFNQSFBY-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).- UPC:
- 51000000
- Condition:
- New
- HazmatClass:
- No
- MPN:
- C1305-100MG
- CAS:
- 81760-48-7
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