C-REACTIVE PROTEIN HUMAN ASCITES

General description

M.W. 23,000 (monomer); 115,000 (pentamer).

Native C-reactive protein from human ascites. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca²⁺-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.

Native C-reactive protein from human ascites. Major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca²⁺-dependent binding to a variety of substrates. Important in the diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. 21 kDa) aggregates as a cyclic pentamer.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 20 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 7.5.

Preparation Note

Prepared from ascites that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Analysis Note

Single band by SDS-PAGE

Other Notes

Christner, R.B., and Mortensen, R.F. 1994. J. Biol. Chem. 269, 9760.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Quality Level: 100. form: liquid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze. solubility: water: soluble. shipped in: wet ice. storage temp.: 2-8°C. Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.