Bucindolol is a non-selective β-adrenoceptor antagonist with additional α1-adrenoceptor blocking activity. Bucindolol acts on both β1 and β2 receptors. The Ki values are 1.61, 1.20 and 68.9 nM for β1-, β2- and α1-adrenoceptors respectively. Bucindolol also acts as a weak 5-HT2A/2B antagonist. Bucindolol displays vasodilatory and antihypertensive actions. Bucindolol can function with β-blockers in formulations to manage chronic heart failure.
Specification: Moligand™, ≥98%
Molecular Formula: C22H25N3O2
Molecular Weight: 363.45
PubChem CID: 51045
Isomeric SMILES: CC(C)(CC1=CNC2=CC=CC=C21)NCC(COC3=CC=CC=C3C#N)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/B335105-SCI_1e6af09c619ed4d42d7610859b45ab86.pdf
- UPC:
- 10161617
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B335105-25mg
- CAS:
- 71119-11-4
- Product Size:
- 25mg
- Precautionary Statement Codes:
- P264
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