BROMOCRESOL GREEN SODIUM SALT & (C005B-053786)

General description

Bromocresol Green (BCG), also known as bromcresol green, is a synthetic, anionic, triphenylmethane dye belonging to the phthalein and sulphonphthalein dyes group. It is commonly used as a pH indicator as it changes color from yellow to blue-green at pH 3.8-5.4. The monosodium salt of bromocresol green is highly ionizable in water. The dye at a higher pH level produces a large and weakly lipophilic dianion.

Application

Bromocresol green serves as a pH indicator in biology and medicinal experiments.

• It is used widely as a vital stain to study blood-brain permeability.
• It is used as a tracking dye for DNA agarose gel electrophoresis, in protein determinations, and in charge-transfer complexation processes.
• It is used in TLC for the visualization of compounds with functional groups whose pKa is below 5.0.
• It has been used in the pH-sensitive colorimetric determination of glutamate decarboxylase activity.
• It has also been employed in the evaluation of paper-analytical devices for colorimetric analysis of serum samples.
• It is suitable as a selective inhibitor in kidney physiology studies.

Molecular Weight: 720.00. Empirical Formula: C₂₁H₁₃Br₄NaO₅S. grade: ACS reagent. Quality Level: 200. Assay: 90% (HPLC). form: powder or crystals. composition: Dye content, 90% . visual transition interval: 3.8-5.2, yellow to blue. mp: 230 . °C (dec.) (lit.). application(s): diagnostic assay manufacturing
hematology
histology. storage temp.: room temp. SMILES string: [Na+].Cc1c(Br)c(O)c(Br)cc1\C(: C2\C: C(Br)C(: O)C(Br): C2C)c3ccccc3S([O-])(: O): O. InChI: 1S/C21H14Br4O5S.Na/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21. /h3-8,26-27H,1-2H3. /q. +1/p-1. InChI key: HEFSGAHJDGZCHA-UHFFFAOYSA-M. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).