BRL-54443 (C007B-067612)

Catalog No.: C007B-067612
Manufacturer No.: B409219-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationBRL 54443 is a5-HT1Eand5-HT1Freceptor agonist withpKiof 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.In vitroBRL 54443 has also measurable affinity for the 5-HT2A receptor. BRL 54443 induces contraction with a −logEC50 of 6.52. Contraction caused by BRL 54443 is likely mediated through stimulation of 5-HT5-HT2A receptors.In vivoBRL 54443 induces an immediate dose-dependent maximal intragastric volume increase vs. saline.Cell Datacell lines：Renca or 786-O cells, mouse endothelial cells and splenic CD11b+/c-myeloid cells, HUVECsConcentrations：Incubation Time：Powder Purity:≥99%.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C14H18N2O

Molecular Weight: 230.31

UPC:: 12141915
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: B409219-1ml
CAS:: 57477-39-1
Product Size:: 1ml

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