Product descriptionBrevilin A (6-O-Angeloylplenolina), a sesquiterpene lactone isolated from Centipeda minima, is a selective inhibitor of STAT3 and attenuates the JAKs activity by blocking the JAKs tyrosine kinase domain JH1. Brevilin A induces apoptosis and autophagy of colon adenocarcinoma cell CT26 via mitochondrial pathway and PI3K/AKT/mTOR inactivation.Targets:STAT3; JAK.
Specifications and Purity: ≥98%
Molecular Formula: C2OH26O5
Molecular Weight: 346.42
PubChem CID: 12302076
Isomeric SMILES: C/C=C(/C)/C(=O)O[C@H]1[C@@H]2[C@@H](C(=O)O[C@@H]2C[C@H]([C@H]3[C@]1(C(=O)C=C3)C)C)C
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/B413675-SCI_f6a7491df2543ab0558b0be59c4b7a89.pdf
- UPC:
- 42211906
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B413675-1mg
- CAS:
- 16503-32-5
- Product Size:
- 1mg
- Hazard Statement Codes:
- H335:H319:H315
- Precautionary Statement Codes:
- P305+P351+P338:P261
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