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BQU57 (C007B-068063)

Catalog No.
C007B-068063
Manufacturer No.
B413791-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

InformationBQU57 BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA.TargetsGTPase RalIn vitroIn both the H2122 and H358 cell lines, BQU57 inhibits both RalA and RalB activation, and thus causes cell

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InformationBQU57 BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA.TargetsGTPase RalIn vitroIn both the H2122 and H358 cell lines, BQU57 inhibits both RalA and RalB activation, and thus causes cell growth inhibition.In vivoIn mice bearing human lung H2122 tumors, BQU57 (50 mg/kg, i.p.) significantly inhibits activation of both RalA and RalB, and causes dose-dependent tumor growth inhibition.Cell Research(from reference)Cell lines:Human lung cancer lines, H2122, H358, H460 and Calu6 Concentrations:~10 μM Incubation Time:48 hours.

Specifications and Purity: ≥98%

Molecular Formula: C16H13F3N4O

Molecular Weight: 334.1

PubChem CID: 77845606

Isomeric SMILES: CC1=NN(C2=C1C(C(=C(O2)N)C#N)C3=CC=C(C=C3)C(F)(F)F)C

UPC:
51131614
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
B413791-25mg
CAS:
1637739-82-2
Product Size:
25mg

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