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bpv(hopic) - calbiochem

BPV(HOPIC)

Catalog No.
C005B-097687
Manufacturer No.
203701-5MG
Manufacturer Name
Calbiochem
Quantity
5
Unit of Measure
MG

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A potent phosphotyrosine phosphatase inhibitor. Activates the insulin receptor kinase (IRK) of hepatoma cells.

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General description

A potent phosphotyrosine phosphatase inhibitor. Activates the insulin receptor kinase (IRK) of hepatoma cells. Also stimulates lipogenesis in isolated adipocytes. Also reported to potently inhibit PTEN (IC50 = 14 nM).

Biochem/physiol Actions

Cell permeable: no

Primary Target
PTEN

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Other Notes

Schmid, A.C., et al. 2004. FEBS Lett.566, 35.
Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

linearFormula: K2[VO(O2)2C6H4NO3] · 4H2O. Quality Level: 100. Assay: ≥. 70% (51V-NMR). form: solid. potency: 14 . nM IC50. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze, protect from light. color: yellow. solubility: water: 4 . mg/mL. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
12141706
Condition:
New
HazmatClass:
No
MPN:
203701-5MG

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