BONE MORPHOGENETIC PROTEIN 7 RECOMBINANT HUMAN

Biochem/physiol Actions

Cellular responses to BMP-7 are mediated by the formation of hetero-oligomeric complexes of type I and II serine/threonine kinase receptors. Human and mouse BMP-7 share 98% amino acid sequence identity.

Physical form

Lyophilized from 50.0 μl of a 0.2 μm filtered solution in 35% acetonitrile, 0.1% TFA containing 50 μg bovine serum albumin per 1μg of cytokine.

Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production using mouse ATDC-5 chondrogenic cells.

biological source: human. Quality Level: 100. recombinant: expressed in CHO cells. Assay: >. 95% (SDS-PAGE). form: lyophilized powder. potency: 0.2-0.6 . μ. g/mL ED₅₀. mol wt: monomer calculated mol wt 15.7 . kDa, 18-20 . kDa by SDS-PAGE (reducing), 30-40 . kDa by SDS-PAGE (non-reducing). packaging: pkg of 10 . μ. g. storage condition: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.). technique(s): cell culture | mammalian: suitable. impurities: endotoxin, tested. UniProt accession no.: P18075. storage temp.: −. 20°C. Gene Information: human ... BMP7(655). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319. Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.