Biochem/physiol Actions
Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.
Physical form
Lyophilized from a 0.2 μm filtered buffered solution containing 0.5 mg bovine serum albumin.
Analysis Note
The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.
biological source: human. Quality Level: 200. recombinant: expressed in E. coli. Assay: ≥. 98% (SDS-PAGE). form: lyophilized powder. mol wt: 26 . kDa. packaging: pkg of 10 . μ. g. storage condition: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.). technique(s): cell culture | mammalian: suitable. impurities: endotoxin, tested. color: white. solubility: water: soluble 0.100 . mL, clear, colorless. UniProt accession no.: P12643. storage temp.: −. 20°C. Gene Information: human ... BMP2(650). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51182410
- Condition:
- New
- HazmatClass:
- No
- MPN:
- B3555-10UG
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