BOC-GLU(OCHX)-OH 25 G

General description

Standard building block for introduction of glutamic acid in Boc SPPS. This side-chain protecting group for glutamic acid is used to minimize side reactions during acidic and basic treatments ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] J. P. Tam, et al. (1979) Tetrahedron Lett., 42, 4033.

Linkage

Replaces: 04-12-0121

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -9.0 - -7.0 °
Purity (TLC(0811)): ≥ 98 %
Purity (DC (0157)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 329.39. Empirical Formula: C₁₆H₂₇NO₆. Quality Level: 200. product line: Novabiochem^®. . Assay: ≥. 98% (TLC). form: powder. reaction suitability: reaction type: Boc solid-phase peptide synthesis. manufacturer/tradename: Novabiochem^®. . mp: 54-57 . °C. application(s): peptide synthesis. functional group: carboxylic acid. storage temp.: 2-30°C. InChI: 1S/C16H27NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-10-13(18)22-11-7-5-4-6-8-11/h11-12H,4-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1. InChI key: FDNMLANBNJDIRG-LBPRGKRZSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.