BISBENZIMIDE HOECHST NO 33258 TRIHYDROCHLORIDE (C005B-026532)

Application

bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. = 346 nm
Emission max. = 460 nm

bisBenzimide H 33258 has been used for nuclear staining in cells.

Biochem/physiol Actions

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.

Molecular Weight: 533.88. Empirical Formula: C₂₅H₂₄N₆O · 3HCl. Quality Level: 200. Assay: ≥. 98% (HPLC and TLC). form: powder. mp: 280 . °C. solubility: H₂O: 10 . mg/mL, water and ethanol: 10 . mg/mL, phosphate buffer: precipitates. suitability: passes application test for fluorescence. application(s): diagnostic assay manufacturing
hematology
histology. storage temp.: −. 20°C. SMILES string: Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(: NCc3c2)c4ccc5NC(: NCc5c4)c6ccc(O)cc6. InChI: 1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18. . . . /h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31). 3*1H. 1H2. InChI key: OWRSPPSBNWJJAR-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.