Bis-Tris, Biologics Grade (C062B-049103)

Bis-Tris, Biologics Grade buffer from ANGUS Chemical Company is a 99.0% pure buffering agent widely used as a diagnostic reagent and in gel electrophoresis separations, cell culture and bioprocessing applications. BIS-TRIS is ideal for a variety of biological-based formulations and nucleic acid systems and is known to complex with various metals. • High purity, 99.0% • Produced under a single global quality system that includes ISO 9001:2015 • Proven safe use in commercial drug products • Highly soluble in water • Ideal for use as an alternative to cacodylate, maleic acid and citrate Uses and Applications • Purification of biological molecules (downstream processing) • Raw materials for API/drug substance formulation • Cell culture buffer • Fractionation of hemoglobin • Gel electrophoresis • Diagnostic reagents • Research and development buffer (R&D) • Analytical chromatography • Non-sterile excipient Typical Properties* Purity: 99.9% Molecular weight: 209.24 Melting point: 100.0 – 104.0°C pH (1.0M aqueous solution @25°C): 9.5 – 11.0 Working pH Range: 5.8 – 7.2 pKa @ 20°C: 6.35 – 6.65 *Values shown are typical properties and are not to be considered product specifications. Test methods available upon request.

Shipping Information: Tariff No. 2915905050

More Information: https://www.spectrumchemical.com/media/sds/37604_SDS.pdf