BI-9627 (C007B-335791)

Catalog No.: C007B-335791
Manufacturer No.: B646988-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

BI-9627 is potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC 50 s of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. BI-9627 displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. BI-9627 shows low DDI (agent-agent interaction) potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injuryForm:SolidIC50& Target:IC50: 6 nM (NHE1 in intracellular pH recovery assay), 31 nM (NHE1 in human platelet swelling assay).

Specifications and Purity: ≥98%

Molecular Formula: C16H19F3N4O2

Molecular Weight: 356.34

PubChem CID: 121513866

UPC:: 41113105
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: B646988-5mg
CAS:: 1204329-34-9
Product Size:: 5mg

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