BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.A potent and selective inhibitor of Flg (FGFR-1), Bek (FGFR-2), FGFR-3 and FGFR-4.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C26H31Cl2N7O3
Molecular Weight: 560.48
PubChem CID: 53235510
Isomeric SMILES: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
- UPC:
- 41106223
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B426598-1ml
- CAS:
- 872511-34-7
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





