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betulinic acid (c15-1240-570)

BETULINIC ACID TECH. 90% (C005B-041302)

Catalog No.
C005B-041302
Manufacturer No.
855057-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG

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Betulinic acid is a lupane-type triterpene, which can be prepared from betulin via oxidation using chromium oxide (VI). Along with anti-HIV-1 and anti-tumor activity, it also shows other bioactivities such as anti-inflammatory, antibacterial, in

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General description

Betulinic acid is a lupane-type triterpene, which can be prepared from betulin via oxidation using chromium oxide (VI). Along with anti-HIV-1 and anti-tumor activity, it also shows other bioactivities such as anti-inflammatory, antibacterial, in vitro antimalarial, anthelmintic and antioxidant activities.

Biochem/physiol Actions

Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Molecular Weight: 456.70. Empirical Formula: C30H48O3. grade: technical grade. Quality Level: 100. Assay: 90%. form: powder. optical activity: [α. ]20/D +7.8°, c :  . 0.9 in pyridine. mp: 295-298 . °C (dec.) (lit.). storage temp.: 2-8°C. SMILES string: CC(: C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O): O. InChI: 1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1. InChI key: QGJZLNKBHJESQX-FZFNOLFKSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
UPC:
12352202
Condition:
New
HazmatClass:
No
MPN:
855057-100MG
CAS:
472-15-1

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