BETA-ALANINE (C005B-006584)

General description

β-Alanine is a rate-limiting precursor of carnosine, a cytoplasmic dipeptide which is present in human skeletal muscles in high concentrations.

Application

β-Alanine may be used as a reference standard for the determination of β-alanine in:

• Potato tubers by gas chromatography-mass spectrometry (GC-MS).
• Human plasma, urine, and cerebrospinal fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
• Striatal microdialysis samples by high performance liquid chromatography-fluorescence detection (HPLC-FLD) with ortho-phthalaldehyde-mercaptoethanol derivatization.
• Fermented soybean paste, Cheonggukjang, by GC-MS operating in selected-ion monitoring (SIM) mode and principal component analysis (PCA).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Molecular Weight: 89.09. Empirical Formula: C₃H₇NO₂. linearFormula: NH₂CH₂CH₂COOH. grade: analytical standard. Quality Level: 100. Assay: ≥. 98.0% (HPLC). shelf life: limited shelf life, expiry date on the label. analyte chemical class(es): amino acids, peptides, proteins. technique(s): HPLC: suitable, gas chromatography (GC): suitable. impurities: ≤. 0.3% water. color: white to off-white. mp: 202 . °C (dec.) (lit.). application(s): cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care. format: neat. SMILES string: NCCC(O): O. InChI: 1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6). InChI key: UCMIRNVEIXFBKS-UHFFFAOYSA-N. Storage Class Code: 13 - Non Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.