BERGAMOTTIN (C005B-243266)

Catalog No.: C005B-243266
Manufacturer No.: 01338-5MG-F
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: EA

General description Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor.

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Description
Specifications

General description

Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.

Application

Bergamottin may be used as an analytical standard to test its efficacy in the following:

Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.
Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

UPC:: 51111613
Condition:: New
HazmatClass:: No
MPN:: 01338-5MG-F
CAS:: 7380-40-7

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