Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.Appearance:SolidIC50& Target:IC50: 56 nM(B-RAF), 7 nM(B-RAFv 600E ), 5 nM(C-RAF) .In Vitro:Belvarafenib (Example 116) is a potent and pan RAF inhibitor with antineoplastic activity. The IC 50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively. It also shows high inhibitory activity for FMS, DDR1 and DDBiological Activity:Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.
Specifications and Purity: ≥99%
Molecular Formula: C25H17ClF4N6O3S
Molecular Weight: 592.95
- UPC:
- 51111717
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B659018-5mg
- Product Size:
- 5mg
akash.verma@cenmed.com
(732) 447-1115





