BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymesIn VitroBAY-805 inhibits the activity of hUSP21 HTRF and hUSP21 Ub-Rhod with IC 50 values of 6 nM and 2 nM, respectively. BAY-805 (10 µM) induces the NF-κB activation with an EC 50 value of 17 nM. BAY-805 (10 µM and 50 µM) significantly inhibits the activity of USP21 and also shows weak influence on USP22 and USP10. BAY-805 (0.0001-1000000 nM) selectively inhibits the activity of USP21. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:USP21.
Specifications and Purity: ≥99%
Molecular Formula: C24H28F3N5O2S
Molecular Weight: 507.57
- UPC:
- 42295109
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- B649535-5mg
- CAS:
- 2925481-88-3
- Product Size:
- 5mg
akash.verma@cenmed.com
(732) 447-1115





