BAY 61-3606 dihydrochloride (C007B-068048)

Catalog No.: C007B-068048
Manufacturer No.: B413704-25mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

BAY 61-3606 dihydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM an IC50 of 10 nM. BAY 61-3606 dihydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. BAY 61-3606 dihydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates. Bay 61-3606 dihydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.

Specifications and Purity: ≥98%

Molecular Formula: C20H20Cl2N6O3

Molecular Weight: 463.32

PubChem CID: 11784504

Isomeric SMILES: COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl

UPC:: 12142202
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: B413704-25mg
CAS:: 648903-57-5
Product Size:: 25mg

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