BAMBUTEROL HYDROCHLORIDE (C005B-081790)

General description

Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.

Application

Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.

Biochem/physiol Actions

Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.

β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Molecular Weight: 403.90. Empirical Formula: C₁₈H₃₀N₃O₅Cl. linearFormula: C₁₈H₂₉N₃O₅ · HCl. Quality Level: 100. Assay: >. 98% (HPLC). form: powder. storage condition: desiccated. color: off-white. solubility: H₂O: soluble ~33 . mg/mL. originator: AstraZeneca. SMILES string: Cl.CN(C)C(: O)Oc1cc(OC(: O)N(C)C)cc(c1)C(O)CNC(C)(C)C. InChI: 1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7. /h8-10,15,19,22H,11H2,1-7H3. 1H. InChI key: LBARATORRVNNQM-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).