BAM7 is a direct activator of Bax (EC50 = 3.3 µM) that engages the Bax trigger site and promotes the functional oligomerization of Bax. It is selective for the BH3 binding site on Bax and does not interact with BH3 binding pockets on other proteins. BAM7 induces Bax-dependent cell death in mouse embryo fibroblasts.
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- UPC:
- 12131803
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 14566-1
- CAS:
- 331244-89-4
- Model Number:
- C823N09
- Temperature Control Device:
- Yes
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