Name: BACITRACIN FROM BACILLUS LICHENIFORMIS ACTIVITY: >= 60000 U/G (POTENCY) (C005B-017234)
SKU: C005B-017234
Availability: OutOfStock

BACITRACIN FROM BACILLUS LICHENIFORMIS ACTIVITY: >= 60000 U/G (POTENCY) (C005B-017234)

Catalog No.

C005B-017234

Manufacturer No.

11702-25G

Manufacturer Name

Sigma-Aldrich

Quantity

Unit of Measure

Chemical structure: peptide Application Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is also used to study the biosynthesis of sterols and squalene.

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Description
Specifications

General description

Chemical structure: peptide

Application

Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is also used to study the biosynthesis of sterols and squalene.
Bacitracin has been used:

as a protease inhibitor
as a control antibiotic
for the calibration in size exclusion chromatography

Biochem/physiol Actions

Bacitracin has been shown to decrease vancomycin-resistant Enterococcus faecium population in intestine.

Bacitracin is a peptide antibiotic.
Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.

Packaging

5G, 25 G

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

Molecular Weight: 1422.69. Empirical Formula: C₆₆H₁₀₃N₁₇O₁₆S. biological source: Bacillus licheniformis. Quality Level: 200. form: powder. specific activity: ≥. 65 . IU/mg. color: white to pale buff. antibiotic activity spectrum: Gram-positive bacteria. Mode of action: cell wall synthesis | interferes. storage temp.: 2-8Â°C. SMILES string: [H]N1[C@@H](Cc2cnc[nH]2)C(: O)N[C@H](CC(O): O)C(: O)N[C@@H](CC(N): O)C(: O)NCCCC[C@H](NC(: O)[C@@H](NC(: O)[C@@H](CCC(O): O)NC(: O)[C@H](CC(C)C)NC(: O)C3CSC(: N3)C(N)C(C)CC)[C@@H](C)CC)C(: O)N[C@H](CCCN)C(: O)N[C@@H]([C@@H](C)CC)C(: O)N[C@H](Cc4ccccc4)C1: O. InChI: 1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1. InChI key: CLKOFPXJLQSYAH-RNHDWVCBSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).