AVE-0118 is a nonselective Kv1.5 blocker with an IC 50 of 1.1 μM. AVE-0118 is a multichannel inhibitor with weak, micromolar activity against Kv1.5 and other ion channels. It is inactive against I Ks , I KATP , and L-type Ca+ channels .
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AVE-0118 is a nonselective Kv1.5 blocker with an IC 50 of 1.1 μM. AVE-0118 is a multichannel inhibitor with weak, micromolar activity against Kv1.5 and other ion channels. It is inactive against I Ks , I KATP , and L-type Ca+ channels .
PubChem CID: 9811357
Isomeric SMILES: COC1=CC=C(C=C1)CC(=O)NCC2=CC=CC=C2C3=CC=CC=C3C(=O)NCCC4=CN=CC=C4
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