ASP-PHE METHYL ESTER (C005B-026279)

General description

Asp-Phe methyl ester (aspartame, APM, ASP), a dipeptide ester, is made up of phenyl alanine and aspartic acid. Its genotoxic effects have been investigated. Its interaction with certain hydrocolloids has been studied.

Application

Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester.

Biochem/physiol Actions

Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sugar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid factor activity. Asp-Phe methyl ester is being studied for its effect on thrombin activity and blood clotting.

Molecular Weight: 294.30. Empirical Formula: C₁₄H₁₈N₂O₅. linearFormula: HOOCCH₂CH(NH₂)CONHCH(CH₂C₆H₅)COOCH₃. Quality Level: 200. Assay: ≥. 98%. form: powder. sweetness: 160-200 . × sucrose. color: white to off-white. storage temp.: 2-8°C. SMILES string: COC(: O)[C@H](Cc1ccccc1)NC(: O)[C@@H](N)CC(O): O. InChI: 1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1. InChI key: IAOZJIPTCAWIRG-QWRGUYRKSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).