AR420626 (C005B-312242)

Catalog No.: C005B-312242
Manufacturer No.: SML1339-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Biochem/physiol Actions AR420626 is a selective agonist of Free Fatty Acid 3 receptor FFA3 (previously called GPR41). FFA3 is expressed in adipose tissue, gut, and the peripheral nervous system and normally activated by short chain fatty acids

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Description
Specifications

Biochem/physiol Actions

AR420626 is a selective agonist of Free Fatty Acid 3 receptor FFA3 (previously called GPR41). FFA3 is expressed in adipose tissue, gut, and the peripheral nervous system and normally activated by short chain fatty acids (SCFAs) produced in the body through the fermentation of complex carbohydrates by the gut microbiota. There is increasing interest in the role of the various free fatty acid receptors and SCFAs as chemical messengers in energy regulation and regulation of inflammatory processes and as therapeutic targets in the treatment of various metabolic and inflammatory conditions. AR420626 has an EC₅₀ value of 117 nM for FFAR3 and did not activate FFAR2 in concentrations up to 100 μM.

UPC:: 41114406
Condition:: New
HazmatClass:: No
MPN:: SML1339-25MG

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