InformationApilimod (STA-5326) Apilimod (STA-5326) is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibitsIn vitroApilimod selectively inhibits TLR-induced cytokine expression. It selectively inhibits the production of IL12p40, whereas it has little effect on IL8 production in THP-1 cells. Apilimod reduces not only PtdIns(3,5)P2 production but also that of PtdIns5P in intact cells.In vivoCell Datacell lines:Concentrations:10 nM and 1 μMIncubation Time:120 minPowder Purity:≥99%.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C23H26N6O2
Molecular Weight: 418.49
- UPC:
- 42281518
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A408817-1ml
- CAS:
- 541550-19-0
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





