ANHYDROTETRACYCLINE HYDROCHLORIDE (C005B-016619)

General description

Anhydrotetracycline (ATC) is a degradation product of tetracycline hydrochloride, a widely used antibiotic in animal breeding.

Application

The analytical standard can be used as follows:

• Terahertz (THz) spectroscopy-based temperature-dependent quantitative and qualitative analysis of the antibiotic, tetracycline hydrochloride, and its three major metabolites
• Simultaneous analysis of tetracycline hydrochloride and its degradation products in a pharmaceutical formulation by Resonance Raman Spectroscopy to study stress-induced stability of the drug
• Development and validation of a liquid chromatography-tandem mass spectroscopy (LC-MS/MS) method to determine 21 antibiotic residues used as veterinary medicinal products in honey samples
• Estimation of eight tetracycline antibiotics in various environmental water samples by dispersive liquid-liquid microextraction (DLLME) followed by an ultra-high pressure liquid chromatography (UHPLC)-tunable ultraviolet detection (TUV)

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Molecular Weight: 462.88. Empirical Formula: C₂₂H₂₂N₂O₇ · HCl. grade: analytical standard. Quality Level: 100. Agency: EPA 1694. product line: VETRANAL^®. . shelf life: limited shelf life, expiry date on the label. storage condition: under inert gas. technique(s): HPLC: suitable, gas chromatography (GC): suitable. application(s): clinical testing. format: neat. SMILES string: Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(: O)[C@]1(O)C(: O)C(C(N): O): C(O)[C@H]2N(C)C. InChI: 1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28. /h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30). 1H/t11-,16-,22-. /m0./s1. InChI key: XBSQEFHDCDFNJU-WPJNXPDPSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).