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anagyrine

Anagyrine (C007B-324911)

Catalog No.
C007B-324911
Manufacturer No.
A647058-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective

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Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR , and Anagyrine can directly, without metabolism, desensitize nAChR .In VitroAnagyrine acts as a partial agonist in both cell lines with EC 50 values of 4.2 and 231 μM in SH-SY5Y and TE-671 cells, respectively. Anagyrine is a desensitizer of nAChR with DC 50 values of 6.9 and 139 μM in SH-SY5Y and TE-671 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Oil.

Specifications and Purity: ≥97%

Molecular Formula: C15H20N2O

Molecular Weight: 244.33

PubChem CID: 442938

Isomeric SMILES: C1CCN2C[C@@H]3C[C@@H]([C@H]2C1)CN4C3=CC=CC4=O

UPC:
51152011
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
A647058-1mg
CAS:
486-89-5
Product Size:
1mg

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